October 31, 2014

LONGRANGE® (eprinomectin) Beats Conventional Dewormers in Stocker Study

In an industry measured by pounds that translate into dollars, deworming is a must.

Economically, one of the best things producers can do for their cattle is deworm.

Over time, parasites take a toll on reproduction, weight gain and body condition in the herd, so in an industry measured by pounds that translate into dollars, deworming is a must.

In 2012, Merial introduced LONGRANGE® (eprinomectin), the first extended-release injectable cattle dewormer that provides season-long persistent parasite control for up to 100 to 150 days in a single subcutaneous dose, dependent on parasite species.1,2

After a product is released, it’s common to begin making product comparisons, leading Merial veterinarians and researchers to study how LONGRANGE can impact average daily gain (ADG) in cattle herds compared to conventional dewormers.

Throughout the 2013 grazing season, 15,205 steer and heifer stocker calves from multiple locations across the United States were studied on 18 site locations, representing a cross-section of grazing environments and pastures, to determine the effect on ADG of pens of cattle administered a single dose of LONGRANGE compared to other common deworming practices.3

The study proved that cattle treated with LONGRANGEhad a significantly higher (p<0.01) ADG than cattle treated with conventional dewormers.3 This included individual comparisons against DECTOMAX® (doramectin), IVOMEC® (ivermectin)Pour-On, IVOMEC 1% Injection and generic ivermectin pour-on, as well comparisons against the following combinations:

  • DECTOMAX + SAFE-GUARD® (fenbendazole)
  • DECTOMAX + SAFE-GUARD + generic ivermectin pour-on
  • IVOMEC Pour-On + VALBAZEN® (albendazole)
  • CYDECTIN® (moxidectin) + SAFE-GUARD
  • IVERMAX® (ivermectin) + SAFE-GUARD
  • CYDECTIN + SAFE-GUARD

The results yielded an ADG difference of 0.28 lbs./day.3 At today’s prices, that’s an extra $56 per head.

LONGRANGE also demonstrated a higher ADG when broken out between heifers and steers – the difference was 0.22 lbs./day for the heifers* and 0.31 lbs./day for the steers.3

The calves receiving treatment – with average weights ranging from 352 to 786 pounds3 – were studied on operations in nine states: Colorado, Iowa, Idaho, Nebraska, North Dakota, Oregon, Texas, Virginia and Wisconsin.

Animals received health observations regularly at every operation. At each location, animals in Treatment Group 1 (LONGRANGE) and Treatment Group 2 (conventional deworming product(s)) were maintained on separate but similar pastures with similar stocking rates. There were 8,014 calves assigned to Treatment Group 1 and 7,191 calves assigned to Treatment Group 2. Days on pasture ranged from 37 to 154 for Treatment Group 1 and 52 to 154 for Treatment Group 2.3

ADG was calculated for each pasture group by subtracting the average weight in (total weight in by number of animals in) from the average weight out (total weight out divided by number of animals out), and dividing by days on pasture and rounding to the nearest 0.01 pound.3

Because every situation is different, producers should consult their veterinarian to develop a strategic deworming protocol that will meet the specific needs of their operation and herd.

LONGRANGE is available through a prescription from a veterinarian. To learn more about how LONGRANGE can save an operation precious time, money and resources, visit www.theLONGRANGElook.com.

IMPORTANT SAFETY INFORMATION FOR LONGRANGE Do not treat within 48 days of slaughter.Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, or in veal calves. Post-injection site damage (e.g., granulomas, necrosis) can occur. These reactions have disappeared without treatment.

IMPORTANT SAFETY INFORMATION FOR IVOMEC POUR-ON Do not treat cattle within 48 days of slaughter. Do not use in dairy cattle of breeding age or in veal calves. Do not use in other animal species not on the label as severe adverse reactions, including fatalities in dogs, may result.

IMPORTANT SAFETY INFORMATION FOR IVOMEC 1% INJECTION Do not treat cattle within 35 days of slaughter. Do not use in dairy cattle of breeding age or in veal calves. Do not treat swine within 18 days of slaughter. Do not use in other animal species not on the label as severe adverse reactions, including fatalities in dogs, may result.

About Merial

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health, well-being and performance of a wide range of animals. Merial employs approximately 6,200 people and operates in more than 150 countries worldwide with close to €2 billion of sales in 2013.

Merial is a Sanofi company.

For more information, please see www.merial.com.

®LONGRANGE and ®IVOMEC are registered trademarks of Merial. All other marks are property of their respective owners. ©2014 Merial Limited, Duluth, GA. All rights reserved. RUMIELR1473 (08/14).

*Heifer ADG difference not statistically significant

1 Dependent upon parasite species, as referenced in FOI summary and LONGRANGE product label.

2 LONGRANGE product label.

3 Data on file at Merial.